BRADLEY MOORE

Professor
CTR FOR MARINE BIOTEC & BIOMED

Research Interests

  • Marine Biomedicine and Biotechnology
  • Microbial Genomics and Metabolomics
  • Natural Product Drug Discovery
  • Natural Toxins and Pollutants
  • Synthetic Biology

Degrees

  • B.S., University of Hawaii
  • PhD, University of Washington
  • Postdoc, University of Zurich

Recent Publications

Adak, S., Calderone, L. A., Krueger, A., Pandelia, M.-E., & Moore, B. S. (2025). Single-Enzyme Conversion of Tryptophan to Skatole and Cyanide Expands the Mechanistic Competence of Diiron Oxidases. Journal of the American Chemical Society, 147(8), 6326–6331. https://doi.org/10.1021/jacs.4c14573
Ledoux, J.-B., Gomez-Garrido, J., Cruz, F., Camara Ferreira, F., Matos, A., Sarropoulou, X., Ramirez-Calero, S., Aurelle, D., Lopez-Sendino, P., Grayson, N. E., Moore, B. S., Antunes, A., Aguilera, L., Gut, M., Salces-Ortiz, J., Fernández, R., Linares, C., Garrabou, J., & Alioto, T. (2025). Chromosome-Level Genome Assembly and Annotation of Corallium rubrum : A Mediterranean Coral Threatened by Overharvesting and Climate Change. Genome Biology and Evolution, 17(2), evae253. https://doi.org/10.1093/gbe/evae253
Brunson, J. K., Thukral, M., Ryan, J. P., Anderson, C. R., Kolody, B. C., James, C. C., Chavez, F. P., Leaw, C. P., Rabines, A. J., Venepally, P., Fussy, Z., Zheng, H., Kudela, R. M., Smith, G. J., Moore, B. S., & Allen, A. E. (2024). Molecular forecasting of domoic acid during a pervasive toxic diatom bloom. Proceedings of the National Academy of Sciences, 121(40). https://doi.org/10.1073/pnas.2319177121
Adak, S., Ye, N., Calderone, L. A., Duan, M., Lubeck, W., Schäfer, R. J. B., Lukowski, A. L., Houk, K. N., Pandelia, M.-E., Drennan, C. L., & Moore, B. S. (2024). A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nature Chemistry. https://doi.org/10.1038/s41557-024-01603-z
Fallon, T. R., Shende, V. V., Wierzbicki, I. H., Pendleton, A. L., Watervoot, N. F., Auber, R. P., Gonzalez, D. J., Wisecaver, J. H., & Moore, B. S. (2024). Giant polyketide synthase enzymes in the biosynthesis of giant marine polyether toxins. Science, 385(6709), 671–678. https://doi.org/10.1126/science.ado3290