9129767 IWNPIQDK items 1 5 date desc year Moore 1221 https://bsmoore.scrippsprofiles.ucsd.edu/wp-content/plugins/zotpress/
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Alker, A. T., Farrell, M. V., Demko, A. M., Purdy, T. N., Adak, S., Moore, B. S., Sneed, J. M., Paul, V. J., & Shikuma, N. J. (2023). Linking bacterial tetrabromopyrrole biosynthesis to coral metamorphosis. ISME Communications, 3(1), 98. https://doi.org/10.1038/s43705-023-00309-6
Lukowski, A. L., Hubert, F. M., Ngo, T.-E., Avalon, N. E., Gerwick, W. H., & Moore, B. S. (2023). Enzymatic Halogenation of Terminal Alkynes. Journal of the American Chemical Society, 145(34), 18716–18721. https://doi.org/10.1021/jacs.3c05750
Alker, A. T., Farrell, M. V., Aspiras, A. E., Dunbar, T. L., Fedoriouk, A., Jones, J. E., Mikhail, S. R., Salcedo, G. Y., Moore, B. S., & Shikuma, N. J. (2023). A modular plasmid toolkit applied in marine bacteria reveals functional insights during bacteria-stimulated metamorphosis. MBio, e01502-23. https://doi.org/10.1128/mbio.01502-23
Cordoza, J. L., Chen, P. Y.-T., Blaustein, L. R., Lima, S. T., Fiore, M. F., Chekan, J. R., Moore, B. S., & McKinnie, S. M. K. (2023). Mechanistic and Structural Insights into a Divergent PLP-Dependent l -Enduracididine Cyclase from a Toxic Cyanobacterium. ACS Catalysis, 13(14), 9817–9828. https://doi.org/10.1021/acscatal.3c01294
Shin, Y.-H., Im, J. H., Kang, I., Kim, E., Jang, S. C., Cho, E., Shin, D., Hwang, S., Du, Y. E., Huynh, T.-H., Ko, K., Ko, Y.-J., Nam, S.-J., Awakawa, T., Lee, J., Hong, S., Abe, I., Moore, B. S., Fenical, W., … Oh, D.-C. (2023). Genomic and Spectroscopic Signature-Based Discovery of Natural Macrolactams. Journal of the American Chemical Society, 145(3), 1886–1896. https://doi.org/10.1021/jacs.2c11527